CLS

Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo

東京科学大学
総合研究院
化学生命科学研究所

LAST UPDATE 2022/11/04

  • 研究者氏名
    Researcher Name

    ロレンツォ　カッティ　Lorenzo CATTI
    助教　Assistant Professor

  • 所属
    Professional Affiliation

    東京科学大学総合研究院化学生命科学研究所
    Laboratory for Chemistry and Life Science, Institute of Integrated Research, Institute of Science Tokyo

    分子創成化学領域、吉沢・澤田研究室
    Molecular synthesis, Yoshizawa-Sawada Laboratory

  • 研究キーワード
    Research Keywords

    Supramolecular Chemistry
    Polyaromatic Nano-Tools
    Biofunctional Chemistry
    Aqueous Nanoreactors
研究テーマ
Research Subject
Synthesis and Function of Supramolecular Capsules

研究の背景 Background

The bottom-up fabrication of nanostructures from self-assembling building blocks is being heavily studied for the development of next-generation nano-tools. The properties of small molecules are heavily altered within these nanostructures, when compared to conventional glass flasks. Our group has established bent anthracene dimers as emerging building blocks, which allow the formation of water-soluble nanostructures using coordination, covalent and non-covalent bonds.

研究の目標 Outcome

Using bent anthracene dimers as the basis, I aim to develop novel nanocapsules with unique internal and external functionalities. In order to fine-tune the properties of encapsulated guest molecules, or to induce reactions, I plan to install functional groups within these nanocapsules. I furthermore aim to increase the biocompatibility of our nanocapsules in order to advance their bio-applications, including sensing, labeling and drug-delivery.

研究図Research Figure

文献 / Publications

Selected examples: Coord. Chem. Rev. 2022, 460, 214460; J. Am. Chem. Soc. 2021, 143, 9361–9367;
Angew. Chem. Int. Ed. 2020, 59, 11881–11885; Acc. Chem. Res. 2019, 52, 2392–2404; Nature Commun. 2019, 10, 1948;
Angew. Chem. Int. Ed. 2018, 57, 14589–14592.

研究者HP