Research Institute for Electronic Science, Hokkaido University


LAST UPDATE 2022/01/14

  • 研究者氏名
    Researcher Name

    鈴木明大 Akihiro SUZUKI
    准教授 Associate Professor
  • 所属
    Professional Affiliation

    Research Institute for Electronic Science, Hokkaido University

    光科学研究部門 コヒーレント光研究分野
    Laboratory of Coherent X-ray Optics, Section of Photonics and Optical Science
  • 研究キーワード
    Research Keywords

    X-ray free-electron laser (XFEL)
    Coherent diffraction
Research Subject
Coherent X-ray imaging of biological and materials science samples

研究の背景 Background


With the development of microfabrication technologies and computing power as well as X-ray light sources, X-ray nanoimaging research based on coherence has been studied intensively in synchrotron radiation facilities across the world since around 2000. Utilizing the characteristics of X-rays such as penetration power, visualization of atomic and nanostructures that cannot be accessed by other probes is expected.

研究の目標 Outcome

これまでに、微細加工技術で作製したマイクロ液体アレイを用いて、溶液中の金属ナノ粒子や生細胞のイメージングに成功してきた。今後は、超高密度X線レーザーを利用できるイメージングシステムを構築することで、生体超分子やタンパク質の単粒子イメージングに挑む。さらに、sub-10 nmでの磁気構造分析を目標に、X線磁気円二色性に基づいた磁気イメージングも展開する。

We have succeeded in nanoimaging metal nanoparticles and living cells in solution using micro-liquid cell arrays fabricated by microfabrication technology. From now on, we will challenge the single-particle imaging of biological supramolecules and proteins by developing an imaging system that can utilize ultra-high-density X-ray laser pulses. In addition, we will develop a magnetic imaging system based on X-ray magnetic circular dichroism to analyze magnetic structures at sub-10 nm.

研究図Research Figure

Fig.1. (a) Diffraction pattern and (b) reconstructed image of self-assembled gold nanoparticles in solution.

Fig.2. The digital microscopy images of micro-liquid cell arrays for high tilt angles: (a)whole picture and (b) enlarged view of a single window.

Fig.3. (a) An ellipsoidal mirror for a soft X-ray imaging system. (b) The illumination function at the sample position and (c) the sample image recovered through the ptychographic phasing method.

文献 / Publications

Rev. Sci. Instrum., 91, 083706 (2020). AIP Advances, 10, 055219 (2020). App. Phys. Lett., 116, 121102 (2020), Phys. Chem. Chem. Phys, 22, 2622 (2020).