Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology


LAST UPDATE 2020/06/11

  • 研究者氏名
    Researcher Name

    穐田宗隆 Munetaka AKITA
    教授 Professor
  • 所属
    Professional Affiliation

    Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology

    Molecular synthesis
  • 研究キーワード
    Research Keywords

    organometallic chemistry of polycarbon species
    photoredox catalysis: catalytic reactions promoted by sunlight
    supramolecular science based on aromatics
Research Subject
Development of organic photoredox reactions

研究の背景 Background


Utilization of sunlight energy has been one of recent major research targets but little attention has been paid to application to organic synthesis. We have been developing novel catalytic organic reactions based on the unique redox properties of the photoredox catalyst such as [Ru(bipy)3]2+. This system has the following excellent features: 1) The catalytic reactions are promoted by visible light (sunlight) and no fossil fuels is needed. 2) The catalytic reactions are atom-economic with no need of addition of sacrificial reagents. These features make the present photoredox catalytic system green.

研究の目標 Outcome


Photoredox catalysts are activated upon visible light irradiation to generate the excited states with a hole and an electron of higher energy, which work as an oxidant and a reductant, respectively. Combination with subsequent redox processes leads to green catalytic systems. Organic radical species can be generated efficiently by application of the present system to electron-rich and electron-deficient precursors to be converted to useful organic compounds. In particular, the present photoredox system turns out to be highly effective for trifluoromethylation of olefinic substrates as a result of regioselective difunctionalization.

研究図Research Figure

Fig. 1. Principles of photoredox catalysis. Fig. 2. Trifluoromethylation of olefinic substrates by the action of photoredox catalysis Fig. 3. Sunlight-driven reaction.

文献 / Publications

Angew. Chem. Int. Ed. 2012, 51, 9567; Angew. Chem. Int. Ed. 2014, 53, 7144; Synlett 2013, 24, 2492; Top. Catal. 2014, 57, 967; Inorg. Chem. Front. 2014, 1, 562.