Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology


LAST UPDATE 2017/02/26

  • 研究者氏名
    Researcher Name

    田巻孝敬 Takanori TAMAKI
    講師 Lecturer
  • 所属
    Professional Affiliation

    Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology

    Molecular functions
  • 研究キーワード
    Research Keywords

    Systematic material design
    Energy materials
    Chemical Engineering
Research Subject
Systematic material design using biomolecules

研究の背景 Background


We have proposed systematic material design to fully utilize the characteristics of biomolecules in enzymatic biofuel cells and DNAconjugated stimuli-responsive membranes. Enzymatic biofuel cells can use non-toxic fuels like glucose and ethanol, and have the potential to power portable devices. However, their power density is low compared with conventional fuel cells due to their low current density. Another research topic is DNA-conjugated stimuli-responsive membranes that coordinate molecular recognition properties of DNA and actuator properties of thermoresponsive polymer in pores of a porous substrate.

研究の目標 Outcome


The current density of enzymatic biofuel cells can be increased to reach a value comparable with that observed in conventional direct methanol fuel cells, considering the high intrinsic activity of enzymes. The rate-limiting step in enzyme electrodes is overcome by structural control of the electrodes. DNA-conjugated stimuli-responsive membranes are designed to change its permeability in response to the presence of a target molecule recognized by the conjugated DNA.

研究図Research Figure

Fig.1. A high-surface-area biofuel cell electrode made of redox-polymer- grafted carbon black overcomes the rate-limiting step of electron conduction through the redox polymer. Fig.2. Reduction of physical adsorption of enzymes and the immobilization of the enzymes using a method other than physical adsorption increased the current density of biofuel cells.Fig.3. Schematic illustration of DNA-conjugated stimuli-responsive membranes. Molecular recognition of DNA aptamer dissociates dsDNA to ssDNA, which induces aggregation of the conjugate polymer via a decrease in charges around the polymer.

文献 / Publications

J. Electrochem. Soc., 161 (13), H3095 (2014). J. Chem. Eng. Jpn., 47 (8), 704 (2014). Ind. Eng. Chem. Res., 49 (14), 6394 (2010). Polym. Chem., 5 (16), 4612 (2014). Chem. Lett., 42 (12), 1568 (2013). Soft Matter, 9 (12), 3331 (2013).